Publikationen

2022

  1. Schebb NH, Kühn H, Kahnt AS, Rund KM, O'Donnell VB, Flamand N, Peters-Golden M, Jakobsson PJ, Weylandt KH, Rohwer N, Murphy RC, Geisslinger G, FitzGerald GA, Hanson J, Dahlgren C, Alnouri MW, Offermanns S, Steinhilber D. Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? Front Pharmacol. 2022 Mar 2;13:838782. doi: 10.3389/fphar.2022.838782. PMID: 35308198; PMCID: PMC8924552.
  2. Flinspach AN, Zinn S, Zacharowski K, Balaban Ü, Herrmann E, Adam EH. Electroencephalogram-Based Evaluation of Impaired Sedation in Patients with Moderate to Severe COVID-19 ARDS. J Clin Med. 2022 Jun 17;11(12):3494. doi: 10.3390/jcm11123494. PMID: 35743572; PMCID: PMC9224742.
  3. Ruf S, Rajagopal S, Kadnur SV, Hallur MS, Rani S, Kristam R, Swaminathan S, Zope BR, Gondrala PK, Swamy I, Putta VPRK, Kandan S, Zech G, Schreuder H, Rudolph C, Elvert R, Czech J, Birudukota S, Siddiqui MA, Anand NN, Mane VS, Dittakavi S, Suresh J, Gosu R, Ramesh M, Yura T, Dhakshinamoorthy S, Kannt A. Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep. 2022 Sep 14;12(1):15440. doi: 10.1038/s41598-022-19634-2. PMID: 36104373; PMCID: PMC9474883.
  4. Schiffmann S, Gunne S, Ulshöfer T, Henke M, Roser LA, Schneider AK, Cinatl J, Thomas D, Schreiber Y, Wagner PV, Grünweller A, Parnham MJ. In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol. Pharmaceuticals (Basel). 2022 Aug 31;15(9):1086. doi: 10.3390/ph15091086. PMID: 36145307; PMCID: PMC9502993.
  5. de Bruin N, Schneider AK, Reus P, Talmon S, Ciesek S, Bojkova D, Cinatl J, Lodhi I, Charlesworth B, Sinclair S, Pennick G, Laughey WF, Gribbon P, Kannt A, Schiffmann S. Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection. Int J Mol Sci. 2022 Jan 19;23(3):1049. doi: 10.3390/ijms23031049. PMID: 35162972; PMCID: PMC8835123.
  6. Erkoc P, von Reumont BM, Lüddecke T, Henke M, Ulshöfer T, Vilcinskas A, Fürst R, Schiffmann S. The Pharmacological Potential of Novel Melittin Variants from the Honeybee and Solitary Bees against Inflammation and Cancer. Toxins (Basel). 2022 Nov 22;14(12):818. doi: 10.3390/toxins14120818. PMID: 36548715; PMCID: PMC9786170.

 

 

2023

1. Gunne S, Schwerdtner M, Henke M, Schneider AK, Keutmann L, Böttcher-Friebertshäuser E, Schiffmann S. TMPRSS2 Impacts Cytokine Expression in Murine Dendritic Cells. Biomedicines. 2023 Feb 1;11(2):419. doi: 10.3390/biomedicines11020419. PMID: 36830955; PMCID: PMC9952936.

2. Sutandy FXR, Gößner I, Tascher G, Münch C. A cytosolic surveillance mechanism activates the mitochondrial UPR. Nature. 2023 Jun;618(7966):849-854. doi: 10.1038/s41586-023-06142-0. Epub 2023 Jun 7. PMID: 37286597; PMCID: PMC10284689.

 

Kontakt

Contact Press / Media

PD Dr. Aimo Kannt

Forschungsbereichsleiter Drug Discovery

Fraunhofer-Institut für Translationale Medizin und Pharmakologie
65926 Frankfurt am Main, Deutschland

Contact Press / Media

Dr. Christiane Schönfeld

Projektmanagerin Leistungszentrum TheraNova

Fraunhofer-Institut für Translationale Medizin und Pharmakologie
Frankfurt am Main